Parkinson’s disease: Scientists review male and female differences
The risk of developing Parkinson’s disease is twice as high in males. However, the neurodegenerative condition progresses more quickly in females, who are also more likely to die prematurely because of it.
These are some examples of the roles that biological sex plays in Parkinson’s disease and for which the evidence is increasing.
It appears that not only does the experience of Parkinson’s disease differ between males and females but that there could be differences in the underlying biology.
Understanding the sex-related differences among people with Parkinson’s disease could help doctors tailor treatments more effectively and improve patient care, says a team of scientists from the Laboratory of Cellular and Molecular Neurobiology at the IRCCS Mondino Foundation, in Pavia, Italy.
To this end, they have summarized the latest knowledge about sex-related differences in Parkinson’s disease in a recent review that features in the Journal of Parkinson’s Disease.
“It is becoming increasingly evident that [Parkinson’s disease] differs in women and men,” says senior study author Dr. Fabio Blandini.
“Recent research findings,” he adds, “suggest that biological sex also impacts on disease risk factors and, potentially, on molecular mechanisms involved in the pathogenesis of [Parkinson’s disease].”
In their review, he and colleagues take a look at how the clinical features, risk factors, biological mechanisms, and responses to the treatment of Parkinson’s disease differ, based on biological sex.
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https://www.medicalnewstoday.com/articles/326483.php